CAMELOT

Study name CAMELOT
Study type multi centre RCT
Brief study description  To establish if the use of rectus sheath catheter (RSC) delivered local anaesthetic (LA) infusion in addition to standard analgesia, is superior to standard analgesia without RSC, as defined by the Overall Benefit of Analgesia Score (OBAS) over the first 5 postoperative days.
Primary outcome(s)  Overall Benefit of Analgesia Score (OBAS) over the first 5 postoperative days. OBAS is a patient-reported composite endpoint of pain scores, opioid side-effects, and patient satisfaction (range 0 [best] to 28 [worst]).
Estimated recruitment target 750
Study start date Jan-23
Estimated completion date Sept-25
Adding centres? Yes
Study URL  https://bristoltrialscentre.blogs.bristol.ac.uk/details-of-studies/camelot/
Study twitter handle @CamelotStudy
PI Mark Edwards
PI email  This email address is being protected from spambots. You need JavaScript enabled to view it.
Co-investigators  Ronelle Mouton

Outcome  

ERASER

Study name ERASER
Study type multi centre RCT
Brief study description   Clinical and Cost Effectiveness of Serratus Anterior Plane Block (SAP) with Catheter Insertion compared to Usual Care in Patients with Multiple Rib Fractures (MRF).
Primary outcome(s)   rates of pneumonia 5 days after randomisation
Estimated recruitment target 824
Study start date Mar-22
Estimated completion date 
Adding centres? Yes
Study URL  https://www.birmingham.ac.uk/research/bctu/trials/portfolio-v/eraser/index.aspx
Study twitter handle 
PI Tony Veenith
PI email  This email address is being protected from spambots. You need JavaScript enabled to view it.
Co-investigators  

Outcome  

Anaesthesia Choice for Creation of Arteriovenous Fistulae (ACCESS)

Star InactiveStar InactiveStar InactiveStar InactiveStar Inactive

Study name Anaesthesia Choice for Creation of Arteriovenous Fistulae (ACCESS)
Study type Multicentre RCT
Brief study description  Adult patients with end stage renal disease (ESRD) who require primary radio- (RCF) or brachio-cephalic fistula (BCF) creation. RA (US guided BPB) vs LA infiltration.
Primary outcome(s) Unassisted functional arteriovenous fistula (AVF) patency at 1 year
Estimated recruitment target 566
Study start date May-21
Estimated completion date Oct-24 Completed
Adding centres? No
Study URL https://fundingawards.nihr.ac.uk/award/NIHR130567
Study twitter handle access_study
PI Emma Aitken
PI email This email address is being protected from spambots. You need JavaScript enabled to view it.
Co-investigators This email address is being protected from spambots. You need JavaScript enabled to view it.. This email address is being protected from spambots. You need JavaScript enabled to view it.

Erector Spinae Plane blocks for the Early Analgesia of Rib fractures in trauma: a multicentre pilot randomised controlled trial with feasibility and embedded qualitative assessment.

Study name Erector Spinae Plane blocks for the Early Analgesia of Rib fractures in trauma: a multicentre pilot randomised controlled trial with feasibility and embedded qualitative assessment.
Study type multicentre feasibility RCT
Brief study description Adult patients admitted to major trauma centres with rib fractures randomised on admission to either ESP catheter plus multimodal analgesia or sham-ESP catheter plus multimodal analgesia
Primary outcome(s) Recruitment and retention rates vs target to determine feasibility of definitive trial
Estimated recruitment target 50
Study start date Nov-21
Estimated completion date Nov-23
Adding centres? No
Study URL nil
Study twitter handle nil
PI David Hewson
PI email This email address is being protected from spambots. You need JavaScript enabled to view it.
Co-investigators This email address is being protected from spambots. You need JavaScript enabled to view it., This email address is being protected from spambots. You need JavaScript enabled to view it., This email address is being protected from spambots. You need JavaScript enabled to view it.

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